Aaron D Gitler : rechercher sur Z-Library

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1

A Template for New Drugs against Alzheimer’s Disease

Aguzzi, Adriano, Gitler, Aaron D.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 453 KB

english, 2013

2

Tie2-Cre–Induced Inactivation of a Conditional Mutant Nf1 Allele in Mouse Results in a Myeloproliferative Disorder that Models Juvenile Myelomonocytic Leukemia

Gitler, Aaron D, Kong, Yi, Choi, John K, Zhu, Yuan, Pear, Warren S, Epstein, Jonathan A

Journal:

Pediatric Research

Année:

2004

Langue:

english

Fichier:

PDF, 789 KB

english, 2004

3

Beer and Bread to Brains and Beyond: Can Yeast Cells Teach Us about Neurodegenerative Disease?

Gitler, Aaron D.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 386 KB

english, 2008

4

ALS Genetics: Gains, Losses, and Implications for Future Therapies

Kim, Garam, Gautier, Olivia, Tassoni-Tsuchida, Eduardo, Ma, X. Rosa, Gitler, Aaron D.

Journal:

Année:

2020

Fichier:

PDF, 3.02 MB

2020

5

Molecular markers of cardiac endocardial cushion development

Aaron D. Gitler, Min Min Lu, Yue Qin Jiang, Jonathan A. Epstein, Peter J. Gruber

Journal:

Developmental Dynamics

Année:

2003

Langue:

english

Fichier:

PDF, 957 KB

english, 2003

6

Discovery and characterization of three novel synuclein genes in zebrafish

Zhihui Sun, Aaron D. Gitler

Journal:

Developmental Dynamics

Année:

2008

Langue:

english

Fichier:

PDF, 650 KB

english, 2008

7

A suite of Gateway® cloning vectors for high-throughput genetic analysis in Saccharomyces cerevisiae

Simon Alberti, Aaron D. Gitler, Susan Lindquist

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 951 KB

english, 2007

8

Model Organisms Reveal Insight into Human Neurodegenerative Disease: Ataxin-2 Intermediate-Length Polyglutamine Expansions Are a Risk Factor for ALS

Nancy M. Bonini, Aaron D. Gitler

Journal:

Journal of Molecular Neuroscience

Année:

2011

Langue:

english

Fichier:

PDF, 317 KB

english, 2011

9

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

Gitler, Aaron D, Chesi, Alessandra, Geddie, Melissa L, Strathearn, Katherine E, Hamamichi, Shusei, Hill, Kathryn J, Caldwell, Kim A, Caldwell, Guy A, Cooper, Antony A, Rochet, Jean-Christophe

Journal:

Nature Genetics

Année:

2009

Langue:

english

Fichier:

PDF, 647 KB

english, 2009

10

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

Yeger-Lotem, Esti, Riva, Laura, Su, Linhui Julie, Gitler, Aaron D, Cashikar, Anil G, King, Oliver D, Auluck, Pavan K, Geddie, Melissa L, Valastyan, Julie S, Karger, David R

Journal:

Nature Genetics

Année:

2009

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2009

11

Nf1 has an essential role in endothelial cells

Gitler, Aaron D., Zhu, Yuan, Ismat, Fraz A., Lu, Min Min, Yamauchi, Yasutaka, Parada, Luis F., Epstein, Jonathan A.

Journal:

Nature Genetics

Année:

2002

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2002

12

Distinct TDP-43 pathology in ALS patients with ataxin 2 intermediate-length polyQ expansions

Michael P. Hart, Johannes Brettschneider, Virginia M. Y. Lee, John Q. Trojanowski, Aaron D. Gitler

Journal:

Acta Neuropathologica

Année:

2012

Langue:

english

Fichier:

PDF, 782 KB

english, 2012

13

The tip of the iceberg: RNA-binding proteins with prion-like domains in neurodegenerative disease

Oliver D. King, Aaron D. Gitler, James Shorter

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.63 MB

english, 2012

14

The modulation of Amyotrophic Lateral Sclerosis risk by Ataxin-2 intermediate polyglutamine expansions is a specific effect

Suzana Gispert, Alexander Kurz, Stefan Waibel, Peter Bauer, Inga Liepelt, Christof Geisen, Aaron D. Gitler, Tim Becker, Markus Weber, Daniela Berg, Peter M. Andersen, Rejko Krüger, Olaf Riess, Albert

Journal:

Neurobiology of Disease

Année:

2012

Langue:

english

Fichier:

PDF, 359 KB

english, 2012

15

Cloning and characterization of zebrafish tbx1

Lazaros K. Kochilas, Vijaya Potluri, Aaron Gitler, Krithika Balasubramanian, Alvin J. Chin

Journal:

Gene Expression Patterns

Année:

2003

Langue:

english

Fichier:

PDF, 481 KB

english, 2003

16

Semaphorin-Plexin Signaling Guides Patterning of the Developing Vasculature

Jesús Torres-Vázquez, Aaron D Gitler, Sherri D Fraser, Jason D Berk, Van N. Pham, Mark C Fishman, Sarah Childs, Jonathan A Epstein, Brant M Weinstein

Journal:

Developmental Cell

Année:

2004

Langue:

english

Fichier:

PDF, 378 KB

english, 2004

17

PlexinD1 and Semaphorin Signaling Are Required in Endothelial Cells for Cardiovascular Development

Aaron D Gitler, Min Min Lu, Jonathan A Epstein

Journal:

Developmental Cell

Année:

2004

Langue:

english

Fichier:

PDF, 902 KB

english, 2004

18

Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives

Kurt A. Engleka, Aaron D. Gitler, Maozhen Zhang, Diane D. Zhou, Frances A. High, Jonathan A. Epstein

Journal:

Developmental Biology

Année:

2005

Langue:

english

Fichier:

PDF, 1021 KB

english, 2005

19

Discovery and characterization of novel synuclein genes in zebrafish

Zhihui Sun, Aaron D. Gitler

Journal:

Developmental Biology

Année:

2008

Langue:

english

Fichier:

PDF, 65 KB

english, 2008

20

TDP-43 toxicity in yeast

Maria Armakola, Michael P. Hart, Aaron D. Gitler

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2011

21

Hop Is an Unusual Homeobox Gene that Modulates Cardiac Development

Fabian Chen, Hyun Kook, Rita Milewski, Aaron D. Gitler, Min Min Lu, Jun Li, Ronniel Nazarian, Robert Schnepp, Kuangyu Jen, Christine Biben, Greg Runke, Joel P. Mackay, Jiri Novotny, Robert J. Schwartz

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 512 KB

english, 2002

22

TDP-43 and FUS/TLS yield a target-rich haul in ALS

Gitler, Aaron D

Journal:

Nature Neuroscience

Année:

2012

Langue:

english

Fichier:

PDF, 744 KB

english, 2012

23

High-throughput Yeast Plasmid Overexpression Screen

Fleming, Michael S., Gitler, Aaron D.

Journal:

Journal of Visualized Experiments

Année:

2011

Langue:

english

Fichier:

PDF, 225 KB

english, 2011

24

Exome sequencing identifies a DNAJB6 mutation in a family with dominantly-inherited limb-girdle muscular dystrophy

Couthouis, Julien, Raphael, Alya R., Siskind, Carly, Findlay, Andrew R., Buenrostro, Jason D., Greenleaf, William J., Vogel, Hannes, Day, John W., Flanigan, Kevin M., Gitler, Aaron D.

Journal:

Neuromuscular Disorders

Année:

2014

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2014

25

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

Kim, Hyung-Jun, Raphael, Alya R, LaDow, Eva S, McGurk, Leeanne, Weber, Ross A, Trojanowski, John Q, Lee, Virginia M-Y, Finkbeiner, Steven, Gitler, Aaron D, Bonini, Nancy M

Journal:

Nature Genetics

Année:

2013

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2013

26

Parallel PARKing: Parkinson’s Genes Function in Common Pathway

Chuang, Rosalind S., Gitler, Aaron D.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 78 KB

english, 2013

27

Evaluating noncoding nucleotide repeat expansions in amyotrophic lateral sclerosis

Figley, Matthew D., Thomas, Anna, Gitler, Aaron D.

Journal:

Neurobiology of Aging

Année:

2014

Langue:

english

Fichier:

PDF, 761 KB

english, 2014

28

TDP-43 in ALS: Stay on Target…Almost There

Jovičić, Ana, Gitler, Aaron D.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 326 KB

english, 2014

29

Congenital muscular dystrophy and generalized epilepsy caused by GMPPB mutations

Raphael, Alya R., Couthouis, Julien, Sakamuri, Sarada, Siskind, Carly, Vogel, Hannes, Day, John W., Gitler, Aaron D.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 3.87 MB

english, 2014

30

A Cellular System that Degrades Misfolded Proteins and Protects against Neurodegeneration

Guo, Lili, Giasson, Benoit I., Glavis-Bloom, Alex, Brewer, Michael D., Shorter, James, Gitler, Aaron D., Yang, Xiaolu

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 4.42 MB

english, 2014

31

Apakaochtodenes A and B: Two Tetrahalogenated Monoterpenes from the Red Marine Alga Portieria hornemannii

Gunatilaka, A. A. Leslie, Paul, Valerie J., Park, Peter U., Puglisi, Melany P., Gitler, Aaron D., Eggleston, Drake S., Haltiwanger, R. Curtis, Kingston, David G. I.

Journal:

Journal of Natural Products

Année:

1999

Langue:

english

Fichier:

PDF, 44 KB

english, 1999

32

Evidence That α-Synuclein Does Not Inhibit Phospholipase D †

Rappley, Irit, Gitler, Aaron D., Selvy, Paige E., LaVoie, Matthew J., Levy, Bruce D., Brown, H. Alex, Lindquist, Susan, Selkoe, Dennis J.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 2.53 MB

english, 2009

33

Yeast genetic screen reveals novel therapeutic strategy for ALS

Figley, Matthew D., Gitler, Aaron D.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 501 KB

english, 2013

34

RNA-binding proteins with prion-like domains in ALS and FTLD-U

Gitler, Aaron D., Shorter, James

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2011

35

GTPase Activity Plays a Key Role in the Pathobiology of LRRK2

Xiong, Yulan, Coombes, Candice E., Kilaru, Austin, Li, Xiaojie, Gitler, Aaron D., Bowers, William J., Dawson, Valina L., Dawson, Ted M., Moore, Darren J., MacDonald, Marcy E.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 3.51 MB

english, 2010

36

Targeted Exon Capture and Sequencing in Sporadic Amyotrophic Lateral Sclerosis

Couthouis, Julien, Raphael, Alya R., Daneshjou, Roxana, Gitler, Aaron D., Gibson, Greg

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 726 KB

english, 2014

37

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

Sun, Zhihui, Diaz, Zamia, Fang, Xiaodong, Hart, Michael P., Chesi, Alessandra, Shorter, James, Gitler, Aaron D., Weissman, Jonathan S.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2011

38

Neurodegeneration: A Leg Up on TDP-43

Figley, Matthew D., Gitler, Aaron D.

Journal:

Current Biology

Année:

2015

Langue:

english

Fichier:

PDF, 463 KB

english, 2015

39

Axonal transport and secretion of fibrillar forms of α-synuclein, Aβ42 peptide and HTTExon 1

Brahic, Michel, Bousset, Luc, Bieri, Gregor, Melki, Ronald, Gitler, Aaron D.

Journal:

Acta Neuropathologica

Année:

2016

Langue:

english

Fichier:

PDF, 2.27 MB

english, 2016

40

Regulating Heart Development: The Role of Nf1

Gitler, Aaron D., Epstein, Jonathan A.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 88 KB

english, 2003

41

There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS

Gitler, Aaron D., Tsuiji, Hitomi

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 936 KB

english, 2016

42

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

Lee, Sebum, Shang, Yulei, Redmond, Stephanie A., Urisman, Anatoly, Tang, Amy A., Li, Kathy H., Burlingame, Alma L., Pak, Ryan A., Jovičić, Ana, Gitler, Aaron D., Wang, Jinhua, Gray, Nathanael S., Seel

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 5.90 MB

english, 2016

43

Semisynthetic and in vitro phosphorylation of alpha-synuclein at Y39 promotes functional partly-helical membrane-bound states resembling those induced by PD mutations

Dikiy, Igor, Fauvet, Bruno, Jovičić, Ana, Mahul-Mellier, Anne-Laure, Desobry, Carole, El-Turk, Farah, Gitler, Aaron D., Lashuel, Hilal A., Eliezer, David

Journal:

ACS Chemical Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2016

44

Analysis of COPII Vesicles Indicates a Role for the Emp47-Ssp120 Complex in Transport of Cell Surface Glycoproteins

Margulis, Neil G., Wilson, Joshua D., Bentivoglio, Christine M., Dhungel, Nripesh, Gitler, Aaron D., Barlowe, Charles

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.90 MB

english, 2016

45

Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia

Jovičić, Ana, Paul, Joseph W., Gitler, Aaron D.

Journal:

Journal of Neurochemistry

Année:

2016

Langue:

english

Fichier:

PDF, 319 KB

english, 2016

46

Defects in trafficking bridge Parkinson's disease pathology and genetics

Abeliovich, Asa, Gitler, Aaron D.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2016

47

Susan Lee Lindquist (1949–2016)

Shorter, James, Gitler, Aaron D.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 155 KB

english, 2016

48

Raise the Roof: Boosting the Efficacy of a Spinal Muscular Atrophy Therapy

Kramer, Nicholas J., Gitler, Aaron D.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 534 KB

english, 2017

49

Cardiac hypertrophy and histone

Kook, Hyun, Lepore, John J, Gitler, Aaron D, Lu, Min Min, Yung, Wendy Wing-man, Mackay, Joel, Zhou, Rong, Ferrari, Victor, Gruber, Peter, Epstein, Jonathan a

Année:

2003

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2003

50

NIH Public Access

Liu-yesucevitz, Liqun, Bassell, Gary J, Gitler, Aaron D, Hart, Anne C, Klann, Eric, Richter, D, Warren, Stephen T, Wolozin, Benjamin

Année:

2012

Langue:

english

Fichier:

PDF, 940 KB

english, 2012